ML133 HCl
CAS No. 1222781-70-5
ML133 HCl( —— )
Catalog No. M17888 CAS No. 1222781-70-5
ML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | Get Quote |
|
| 10MG | 55 | Get Quote |
|
| 25MG | 97 | Get Quote |
|
| 50MG | 156 | Get Quote |
|
| 100MG | 259 | Get Quote |
|
| 200MG | 336 | Get Quote |
|
| 500MG | 566 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameML133 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
DescriptionML133 HCl is a selective potassium channel inhibitor for Kir2.1 with IC50 of 1.8 μM (pH 7.4) and 290 nM (pH 8.5), has no effect on Kir1.1 and weak activity for Kir4.1 and Kir7.1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetCDK
-
RecptorKir2.1
-
Research AreaOthers-Field
-
Indication——
Chemical Information
-
CAS Number1222781-70-5
-
Formula Weight313.82
-
Molecular FormulaC19H19NO·HCl
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 125 mg/mL; 398.32 mM
-
SMILESCl.COC1=CC=C(CNCC2=CC=CC3=C2C=CC=C3)C=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Wang HR, et al. ACS Chem Biol, 2011, 6(8), 845-856.
molnova catalog
related products
-
LY2857785
LY2857785 is a potenrt, reversible and ATP-competitive CDK9 inhibitor with IC50 of 11 nM, also inhibits CDK8 (IC50=16 nM) and weakly inhibits CSK7 (IC50=246 nM).
-
THZ-1 hydrochloride
THZ-1 hydrochloride is a potent, selective, covalent CDK7 inhibitor with IC50 of 3.2 nM; also weakly inhibits CDK12 with IC50 of 250 nM.
-
Butyrolactone I
Butyrolactone I is an ATP-competitive inhibitor of CDK and cdc2 kinase family.
Cart
sales@molnova.com